Rome, 2011. As political institutions are on the brink of collapse, the Vatican is shaken by scandals and it's mayhem on the streets of the Capital.
In the Middle-world, Cinaglia (Filippo Nigro) has tried to take on Samurai’s legacy, and, together with Badali (Emmanuele Aita), he oversees all criminal activity in the city with the support of Adelaide (Paola Sotgiu) and Angelica (Carlotta Antonelli), who are now in command of the Anacleti and Nadia (Federica Sabatini), who helps them managing the dealing spots in Ostia.
But not everyone can accept the established order of things. New key players storm the playing field, upsetting the balance of Rome. It’s the beginning of a revolution, spreading fast from the Church and City Hall to the shores of Ostia, aimed to erase everything that belongs to the past.
Spadino (Giacomo Ferrara) must return home to avoid his own family being eradicated along with it and will have to make new allies, even among people he would’ve never thought could join forces… But war is war and the control of Rome is once again at stake.